Moreover, the scientists identified the ACKR3 receptor at superior concentrations in important brain regions that are also critical opioid activity centers. , showed that a plant-derived compound called conolidine may possibly function to enhance opioid peptides’ soreness-regulating action, suggesting that it could be a safer alternative to opioid medicines. https://www.proleviate.com/post/the-new-pain-killer-conolidine