Unlike CB2, CB1 receptors are affiliated to Specific membrane microdomains, named “lipid rafts” (LR) that modulate CB1-dependent signaling pathways. The practical romance in between CB1 and LR is afflicted by cholesterol written content; specifically, membrane cholesterol enrichment in both Principal and immortalized cell strains lowers the binding to CB1 and https://accidentliabilitysupport57851.blogdomago.com/31999651/cannabis-fundamentals-explained